Sleeping Beauty transposon system for GDNF overexpression of entrapped stem cells in fibrin hydrogel in a rat model of Parkinson’s disease

There is currently no causal treatment available for Parkinson’s disease (PD). However, the use of glial cell line–derived neurotrophic factor (GDNF) to provide regenerative effects for neurons is promising. Such approaches require translational delivery systems that are functional in diseased tissu...

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Detalles Bibliográficos
Autores principales: Stahn, Laura, Rasińska, Justyna, Dehne, Tilo, Schreyer, Stefanie, Hakus, Aileen, Gossen, Manfred, Steiner, Barbara, Hemmati-Sadeghi, Shabnam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10125957/
https://www.ncbi.nlm.nih.gov/pubmed/36853436
http://dx.doi.org/10.1007/s13346-023-01289-9

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