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A small secreted protein NICOL regulates lumicrine-mediated sperm maturation and male fertility
The mammalian spermatozoa produced in the testis require functional maturation in the epididymis for their full competence. Epididymal sperm maturation is regulated by lumicrine signalling pathways in which testis-derived secreted signals relocate to the epididymis lumen and promote functional diffe...
Autores principales: | Kiyozumi, Daiji, Shimada, Kentaro, Chalick, Michael, Emori, Chihiro, Kodani, Mayo, Oura, Seiya, Noda, Taichi, Endo, Tsutomu, Matzuk, Martin M., Wreschner, Daniel H., Ikawa, Masahito |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10125973/ https://www.ncbi.nlm.nih.gov/pubmed/37095084 http://dx.doi.org/10.1038/s41467-023-37984-x |
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