Structural insights into thrombolytic activity of destabilase from medicinal leech

Destabilase from the medical leech Hirudo medicinalis belongs to the family of i-type lysozymes. It has two different enzymatic activities: microbial cell walls destruction (muramidase activity), and dissolution of the stabilized fibrin (isopeptidase activity). Both activities are known to be inhibi...

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Detalles Bibliográficos
Autores principales: Marin, Egor, Kornilov, Daniil A., Bukhdruker, Sergey S., Aleksenko, Vladimir A., Manuvera, Valentin A., Zinovev, Egor V., Kovalev, Kirill V., Shevtsov, Mikhail B., Talyzina, Anna A., Bobrovsky, Pavel A., Kuzmichev, Pavel K., Mishin, Alexey V., Gushchin, Ivan Y., Lazarev, Vassili N., Borshchevskiy, Valentin I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126035/
https://www.ncbi.nlm.nih.gov/pubmed/37095116
http://dx.doi.org/10.1038/s41598-023-32459-x

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