Cargando…

The combined signatures of the tumour microenvironment and nucleotide metabolism-related genes provide a prognostic and therapeutic biomarker for gastric cancer

The tumour microenvironment (TME) is vital to tumour development and influences the immunotherapy response. Abnormal nucleotide metabolism (NM) not only promotes tumour cell proliferation but also inhibits immune responses in the TME. Therefore, this study aimed to determine whether the combined sig...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Jifeng, Zhong, Lei, Deng, Dawei, Zhang, Yunshu, Yuan, Qihang, Shang, Dong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126105/ https://www.ncbi.nlm.nih.gov/pubmed/37095256 http://dx.doi.org/10.1038/s41598-023-33213-z

Ejemplares similares

Oxidative stress and autophagy-mediated immune patterns and tumor microenvironment infiltration characterization in gastric cancer
por: Liu, Jifeng, et al.
Publicado: (2023)

A novel prognostic and therapeutic target biomarker based on necroptosis-related gene signature and immune microenvironment infiltration in gastric cancer
por: Xin, Dao, et al.
Publicado: (2022)

A Nucleotide Metabolism-Related Gene Signature for Risk Stratification and Prognosis Prediction in Hepatocellular Carcinoma Based on an Integrated Transcriptomics and Metabolomics Approach
por: Wei, Tianfu, et al.
Publicado: (2023)

Identifying prognostic signatures in the microenvironment of prostate cancer
por: Lu, Guoliang, et al.
Publicado: (2021)

Single-cell sequencing and bulk RNA sequencing reveal a cell differentiation-related multigene panel to predict the prognosis and immunotherapy response of hepatocellular carcinoma
por: Liu, Jifeng, et al.
Publicado: (2023)

Identification and validation of tumor microenvironment-related prognostic biomarkers in breast cancer
por: Zhong, Shanliang, et al.
Publicado: (2021)

Prognostic Implications of Novel Gene Signatures in Gastric Cancer Microenvironment
por: Sun, Mengyu, et al.
Publicado: (2020)

Characterizing heterogeneity of non‐small cell lung tumour microenvironment to identify signature prognostic genes
por: Mi, Kai, et al.
Publicado: (2020)

Identification and verification of the ferroptosis- and pyroptosis-associated prognostic signature for low-grade glioma
por: Wang, Jie, et al.
Publicado: (2022)

Identification of the Real Hub Gene and Construction of a Novel Prognostic Signature for Pancreatic Adenocarcinoma Based on the Weighted Gene Co-expression Network Analysis and Least Absolute Shrinkage and Selection Operator Algorithms
por: Yuan, Qihang, et al.
Publicado: (2021)

Immune-related potential biomarkers and therapeutic targets in coronary artery disease
por: Liu, Chaosheng, et al.
Publicado: (2023)

The combined signatures of telomere and immune cell landscape provide a prognostic and therapeutic biomarker in glioma
por: Han, Xu, et al.
Publicado: (2023)

Analysis of therapeutic targets and prognostic biomarkers of CXC chemokines in cervical cancer microenvironment
por: Kong, Weina, et al.
Publicado: (2021)

CBXs-related prognostic gene signature correlates with immune microenvironment in gastric cancer
por: Zhang, Yin Jiang, et al.
Publicado: (2022)

The Ferroptosis-Related Noncoding RNA Signature as a Novel Prognostic Biomarker in the Tumor Microenvironment, Immunotherapy, and Drug Screening of Gastric Adenocarcinoma
por: Chen, Xinming, et al.
Publicado: (2021)

Comprehensive characterization of extracellular matrix-related genes in PAAD identified a novel prognostic panel related to clinical outcomes and immune microenvironment: A silico analysis with in vivo and vitro validation
por: Chen, Xu, et al.
Publicado: (2022)

Identification of prognostic gene expression signatures based on the tumor microenvironment characterization of gastric cancer
por: Sang, Qingqing, et al.
Publicado: (2022)

Identification of Therapeutic Targets and Prognostic Biomarkers among Genes from the Mediator Complex Family in the Hepatocellular Carcinoma Tumour-Immune Microenvironment
por: Tan, Wei, et al.
Publicado: (2022)

ZNF385A and ZNF346 Serve as Prognostic Biomarkers Associated with an Inflamed Immunosuppressive Tumor Microenvironment in Hepatocellular Carcinoma
por: Peng, Qihang, et al.
Publicado: (2023)

The role of tumour microenvironment in gastric cancer angiogenesis
por: Brzozowa, Marlena, et al.
Publicado: (2014)

Identification of a novel tumour microenvironment‐based prognostic biomarker in skin cutaneous melanoma
por: Yang, Rong‐Hua, et al.
Publicado: (2021)

Combined signature of N7-methylguanosine regulators with their related genes and the tumor microenvironment: a prognostic and therapeutic biomarker for breast cancer
por: Li, Tingjun, et al.
Publicado: (2023)

Prognostic value of LRRC4C in Colon and Gastric Cancers correlates with Tumour Microenvironment Immunity
por: Yang, XiaoFeng, et al.
Publicado: (2021)

Editorial: Profiling the tumour microenvironment to unveil biomarkers and develop novel therapeutics for cancer therapy
por: Jaillon, Sebastien, et al.
Publicado: (2023)

Development and Validation of a Three-Gene Prognostic Signature Based on Tumor Microenvironment for Gastric Cancer
por: Wang, Qian, et al.
Publicado: (2022)

Autophagy-related prognostic signature characterizes tumor microenvironment and predicts response to ferroptosis in gastric cancer
por: Li, Haoran, et al.
Publicado: (2022)

A novel RNA modification prognostic signature for predicting the characteristics of the tumor microenvironment in gastric cancer
por: Jing, Qiangan, et al.
Publicado: (2023)

Liver metastasis from colorectal cancer: pathogenetic development, immune landscape of the tumour microenvironment and therapeutic approaches
por: Wang, Yaxian, et al.
Publicado: (2023)

Metabolomics study identified bile acids as potential biomarkers for gastric cancer: A case control study
por: Pan, Chen, et al.
Publicado: (2022)

Integrated analysis of Helicobacter pylori-related prognostic gene modification patterns in the tumour microenvironment of gastric cancer
por: Zheng, Kaitian, et al.
Publicado: (2022)

Immune-infiltration based signature as a novel prognostic biomarker in gastrointestinal stromal tumour
por: Wei, Zhe-Wei, et al.
Publicado: (2020)

Prognostic significance and immune infiltration of microenvironment-related signatures in pancreatic cancer
por: Lu, Qian, et al.
Publicado: (2021)

CXC Chemokines as Therapeutic Targets and Prognostic Biomarkers in Skin Cutaneous Melanoma Microenvironment
por: Zhou, Xuezhi, et al.
Publicado: (2021)

Identification of Cuproptosis-Related Subtypes, Establishment of a Prognostic Signature and Characterization of the Tumor Microenvironment in Gastric Cancer
por: Li, Jiazheng, et al.
Publicado: (2023)

The combined signatures of hypoxia and cellular landscape provides a prognostic and therapeutic biomarker in hepatitis B virus‐related hepatocellular carcinoma
por: Chen, Shipeng, et al.
Publicado: (2022)

The combined signatures of G protein-coupled receptor family and immune landscape provide a prognostic and therapeutic biomarker in endometrial carcinoma
por: Chen, Shengyue, et al.
Publicado: (2023)

Clonal architecture in mesothelioma is prognostic and shapes the tumour microenvironment
por: Zhang, Min, et al.
Publicado: (2021)

Identification of lipid metabolism-related biomarkers for diagnosis and molecular classification of atherosclerosis
por: Pan, Xue, et al.
Publicado: (2023)

Understanding the Effects of Radiotherapy on the Tumour Immune Microenvironment to Identify Potential Prognostic and Predictive Biomarkers of Radiotherapy Response
por: Cheng, Shuhui, et al.
Publicado: (2020)

Dissection of the bone marrow microenvironment in hairy cell leukaemia identifies prognostic tumour and immune related biomarkers
por: Koldej, Rachel M., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_lfol8lfo2b3m7d4s9nt7ep89aj