TMEM25 inhibits monomeric EGFR-mediated STAT3 activation in basal state to suppress triple-negative breast cancer progression

Triple-negative breast cancer (TNBC) is a subtype of breast cancer with poor outcome and lacks of approved targeted therapy. Overexpression of epidermal growth factor receptor (EGFR) is found in more than 50% TNBC and is suggested as a driving force in progression of TNBC; however, targeting EGFR us...

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Detalles Bibliográficos
Autores principales: Bi, Jing, Wu, Zhihui, Zhang, Xin, Zeng, Taoling, Dai, Wanjun, Qiu, Ningyuan, Xu, Mingfeng, Qiao, Yikai, Ke, Lang, Zhao, Jiayi, Cao, Xinyu, Lin, Qi, Chen, Xiao Lei, Xie, Liping, Ouyang, Zhong, Guo, Jujiang, Zheng, Liangkai, Ma, Chao, Guo, Shiying, Chen, Kangmei, Mo, Wei, Fu, Guo, Zhao, Tong-Jin, Wang, Hong-Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126118/
https://www.ncbi.nlm.nih.gov/pubmed/37095176
http://dx.doi.org/10.1038/s41467-023-38115-2

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