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Site-specific (68)Ga-labeled nanobody for PET imaging of CD70 expression in preclinical tumor models

BACKGROUND: CD70-CD27 is a costimulatory ligand-receptor pair in the tumor necrosis factor receptor family. With only limited expression in normal tissues, CD70 is constitutively expressed in a variety of solid tumors and hematologic malignancies, facilitating immunosuppression through CD27 signalin...

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Detalles Bibliográficos
Autores principales:	Dewulf, Jonatan, Flieswasser, Tal, Delahaye, Tim, Vangestel, Christel, Miranda, Alan, de Haard, Hans, Jacobs, Julie, Smits, Evelien, Van den Wyngaert, Tim, Elvas, Filipe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126183/ https://www.ncbi.nlm.nih.gov/pubmed/37093350 http://dx.doi.org/10.1186/s41181-023-00194-3

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