Effects of alcohol and PARP inhibition on RNA ribosomal engagement in cortical excitatory neurons

We report on the effects of ethanol (EtOH) and Poly (ADP-ribose) polymerase (PARP) inhibition on RNA ribosomal engagement, as a proxy for protein translation, in prefrontal cortical (PFC) pyramidal neurons. We hypothesized that EtOH induces a shift in RNA ribosomal-engagement (RE) in PFC pyramidal n...

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Detalles Bibliográficos
Autores principales: Krishnan, Harish R., Vallerini, Gian Paolo, Gavin, Hannah E., Guizzetti, Marina, Rizavi, Hooriyah S., Gavin, David P., Sharma, Rajiv P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126255/
https://www.ncbi.nlm.nih.gov/pubmed/37113267
http://dx.doi.org/10.3389/fnmol.2023.1125160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126255/
https://www.ncbi.nlm.nih.gov/pubmed/37113267
http://dx.doi.org/10.3389/fnmol.2023.1125160

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