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Detection of HTLV-1 proviral DNA in cell-free DNA: Potential for non-invasive monitoring of Adult T cell leukaemia/lymphoma using liquid biopsy?

INTRODUCTION: Fragmented genomic DNA is constitutively released from dying cells into interstitial fluid in healthy tissue. In cancer, this so-called ‘cell-free’ DNA (cfDNA) released from dying malignant cells encodes cancer-associated mutations. Thus, minimally invasive sampling of cfDNA in blood p...

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Detalles Bibliográficos
Autores principales:	Joris, Thomas, Haddow, Jana, Taylor, Graham P., Cook, Lucy B. M., Rowan, Aileen G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126272/ https://www.ncbi.nlm.nih.gov/pubmed/37114063 http://dx.doi.org/10.3389/fimmu.2023.1150285

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