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Three-dimensional core-shell alginate microsphere for cancer hypoxia simulation in vitro

Hypoxia is one of the major causes of cancer resistance and metastasis. Currently, it is still lack of convenient ways to simulate the in vivo hypoxic tumor microenvironment (TME) under normoxia in vitro. In this study, based on multi-polymerized alginate, we established a three-dimensional culture...

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Detalles Bibliográficos
Autores principales: Ruan, Yejiao, He, Lingyun, Chen, Jiamin, Wang, Jinfeng, Zhao, Shujing, Guo, Xiaoling, Xie, Yao, Cai, Zhenzhai, Shen, Xian, Li, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126516/
https://www.ncbi.nlm.nih.gov/pubmed/37113672
http://dx.doi.org/10.3389/fbioe.2023.1174206