Cargando…

Chirurgie des alten Menschen – Thoraxchirurgie

BACKGROUND: The incidence of a large number of diseases relevant to thoracic surgery increases with age; however, old age is still frequently considered a contraindication per se for curative interventions and extensive surgical procedures. OBJECTIVE: Overview of the current relevant literature, der...

Descripción completa

Detalles Bibliográficos
Autores principales: Ehrsam, Jonas Peter, Aigner, Clemens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126566/
https://www.ncbi.nlm.nih.gov/pubmed/37251530
http://dx.doi.org/10.1007/s00740-023-00497-w
_version_ 1785030280233353216
author Ehrsam, Jonas Peter
Aigner, Clemens
author_facet Ehrsam, Jonas Peter
Aigner, Clemens
author_sort Ehrsam, Jonas Peter
collection PubMed
description BACKGROUND: The incidence of a large number of diseases relevant to thoracic surgery increases with age; however, old age is still frequently considered a contraindication per se for curative interventions and extensive surgical procedures. OBJECTIVE: Overview of the current relevant literature, derivation of recommendations for patient selection as well as preoperative, perioperative and postoperative optimization. MATERIAL AND METHODS: Analysis of the current study situation. RESULTS: Recent data show that for most thoracic diseases, age alone is not a reason to withhold surgical treatment. Much more important for the selection are comorbidities, frailty, malnutrition and cognitive impairment. A lobectomy or segmentectomy for stage I non-small cell lung cancer (NSCLC) in carefully selected octogenarians can provide acceptable to even comparably good short-term and long-term results as in younger patients. Selected > 75-year-old patients with stages II-IIIA NSCLC even benefit from adjuvant chemotherapy. With appropriate selection high-risk interventions, such as pneumonectomy in > 70-year-old patients and pulmonary endarterectomy in > 80-year-old patients can be performed without an increase in mortality rates. Even lung transplantation can lead to good long-term results in carefully selected > 70-year-old patients. Minimally invasive surgical techniques and nonintubated anesthesia contribute to risk reduction in marginal patients. DISCUSSION: In thoracic surgery the biological age rather than the chronological age is decisive. In view of the increasingly older population, further studies are urgently needed to optimize patient selection, type of intervention, preoperative planning and postoperative treatment as well as the quality of life.
format Online
Article
Text
id pubmed-10126566
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Springer Vienna
record_format MEDLINE/PubMed
spelling pubmed-101265662023-04-27 Chirurgie des alten Menschen – Thoraxchirurgie Ehrsam, Jonas Peter Aigner, Clemens Wien Klin Mag Thoraxchirurgie BACKGROUND: The incidence of a large number of diseases relevant to thoracic surgery increases with age; however, old age is still frequently considered a contraindication per se for curative interventions and extensive surgical procedures. OBJECTIVE: Overview of the current relevant literature, derivation of recommendations for patient selection as well as preoperative, perioperative and postoperative optimization. MATERIAL AND METHODS: Analysis of the current study situation. RESULTS: Recent data show that for most thoracic diseases, age alone is not a reason to withhold surgical treatment. Much more important for the selection are comorbidities, frailty, malnutrition and cognitive impairment. A lobectomy or segmentectomy for stage I non-small cell lung cancer (NSCLC) in carefully selected octogenarians can provide acceptable to even comparably good short-term and long-term results as in younger patients. Selected > 75-year-old patients with stages II-IIIA NSCLC even benefit from adjuvant chemotherapy. With appropriate selection high-risk interventions, such as pneumonectomy in > 70-year-old patients and pulmonary endarterectomy in > 80-year-old patients can be performed without an increase in mortality rates. Even lung transplantation can lead to good long-term results in carefully selected > 70-year-old patients. Minimally invasive surgical techniques and nonintubated anesthesia contribute to risk reduction in marginal patients. DISCUSSION: In thoracic surgery the biological age rather than the chronological age is decisive. In view of the increasingly older population, further studies are urgently needed to optimize patient selection, type of intervention, preoperative planning and postoperative treatment as well as the quality of life. Springer Vienna 2023-04-25 2023 /pmc/articles/PMC10126566/ /pubmed/37251530 http://dx.doi.org/10.1007/s00740-023-00497-w Text en © The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, ein Teil von Springer Nature 2023 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Thoraxchirurgie
Ehrsam, Jonas Peter
Aigner, Clemens
Chirurgie des alten Menschen – Thoraxchirurgie
title Chirurgie des alten Menschen – Thoraxchirurgie
title_full Chirurgie des alten Menschen – Thoraxchirurgie
title_fullStr Chirurgie des alten Menschen – Thoraxchirurgie
title_full_unstemmed Chirurgie des alten Menschen – Thoraxchirurgie
title_short Chirurgie des alten Menschen – Thoraxchirurgie
title_sort chirurgie des alten menschen – thoraxchirurgie
topic Thoraxchirurgie
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126566/
https://www.ncbi.nlm.nih.gov/pubmed/37251530
http://dx.doi.org/10.1007/s00740-023-00497-w
work_keys_str_mv AT ehrsamjonaspeter chirurgiedesaltenmenschenthoraxchirurgie
AT aignerclemens chirurgiedesaltenmenschenthoraxchirurgie