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511 Eliminating System xc- Signaling Between Astrocytes and Neurons Selectively Impairs Complex Cognition

OBJECTIVES/GOALS: We aim to discover safer and more effective therapeutics for CNS disorders. Current therapeutic development is hindered by dosing out drugs for safe consumption. By identifying proteins with narrow functional roles in the brain (i.e., behavioral control), we can develop drugs targe...

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Detalles Bibliográficos
Autores principales: Simandl, Gregory, Simandl, Gregory J., Hess, Evan, Kong, Linghai, Raddatz, Nicholas J., Hurley, Matthew M., Maunze, Brian, Choi, SuJean, Geurts, Aaron M., Baker, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126889/
http://dx.doi.org/10.1017/cts.2023.510