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511 Eliminating System xc- Signaling Between Astrocytes and Neurons Selectively Impairs Complex Cognition
OBJECTIVES/GOALS: We aim to discover safer and more effective therapeutics for CNS disorders. Current therapeutic development is hindered by dosing out drugs for safe consumption. By identifying proteins with narrow functional roles in the brain (i.e., behavioral control), we can develop drugs targe...
Autores principales: | Simandl, Gregory, Simandl, Gregory J., Hess, Evan, Kong, Linghai, Raddatz, Nicholas J., Hurley, Matthew M., Maunze, Brian, Choi, SuJean, Geurts, Aaron M., Baker, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cambridge University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126889/ http://dx.doi.org/10.1017/cts.2023.510 |
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