Cargando…

An in vivo evaluation of clear aligners for optimal orthodontic force and movement to determine high-efficacy and periodontal-friendly aligner staging

OBJECTIVES: To investigate the effect of aligner displacement on tooth movement and periodontal health to improve the efficiency of aligner treatment and explore the mechanism in vivo. METHODS: A two-tooth site was established by a finite element (FE) model to virtually evaluate aligner staging. A r...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yuru, Chen, Jie, Qin, Siwen, Han, Xue, Liao, Lijun, Sima, Xiutian, Guo, Weihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126945/
https://www.ncbi.nlm.nih.gov/pubmed/37113787
http://dx.doi.org/10.1016/j.heliyon.2023.e15317
_version_ 1785030368030621696
author Wang, Yuru
Chen, Jie
Qin, Siwen
Han, Xue
Liao, Lijun
Sima, Xiutian
Guo, Weihua
author_facet Wang, Yuru
Chen, Jie
Qin, Siwen
Han, Xue
Liao, Lijun
Sima, Xiutian
Guo, Weihua
author_sort Wang, Yuru
collection PubMed
description OBJECTIVES: To investigate the effect of aligner displacement on tooth movement and periodontal health to improve the efficiency of aligner treatment and explore the mechanism in vivo. METHODS: A two-tooth site was established by a finite element (FE) model to virtually evaluate aligner staging. A randomized controlled experiment was conducted when the tooth sites in beagles were treated with fixed or aligner appliances with different movement and force, and tooth movement and internal structure were recorded during the alignment. After sacrificing five dogs, bone-periodontal ligament (PDL)-tooth specimens were removed and processed to conduct uniaxial compression and tensile tests as well as micro-CT imaging and histological analysis. RESULTS: Three displacements of 0.25, 0.35 and 0.45 mm were obtained from FE analysis and applied in beagles. In general, aligners had poorer performance on movement compared to fixed systems in vivo, but the aligner with a staging of 0.35 mm had the highest accuracy (67.46%) (P < 0.01). Loaded with severe force, fixed sites exhibited tissue damage due to excess force and rapid movement, while aligners showed better safety. The PDL under a 0.35-mm aligner treatment had the highest elastic modulus in the biomechanical test (551.4275 and 1298.305 kPa) (P < 0.05). CONCLUSIONS: Compared to fixed appliances, aligners achieve slightly slower movement but better periodontal condition. Aligners with an interval of 0.35 mm have the highest accuracy and best PDL biomechanical and biological capacities, achieving the most effective and safest movement. Even with complexity of oral cavity and lack of evaluation of other factors, these results provide insight into faster displacement as a method to improve the efficacy of aligners.
format Online
Article
Text
id pubmed-10126945
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-101269452023-04-26 An in vivo evaluation of clear aligners for optimal orthodontic force and movement to determine high-efficacy and periodontal-friendly aligner staging Wang, Yuru Chen, Jie Qin, Siwen Han, Xue Liao, Lijun Sima, Xiutian Guo, Weihua Heliyon Research Article OBJECTIVES: To investigate the effect of aligner displacement on tooth movement and periodontal health to improve the efficiency of aligner treatment and explore the mechanism in vivo. METHODS: A two-tooth site was established by a finite element (FE) model to virtually evaluate aligner staging. A randomized controlled experiment was conducted when the tooth sites in beagles were treated with fixed or aligner appliances with different movement and force, and tooth movement and internal structure were recorded during the alignment. After sacrificing five dogs, bone-periodontal ligament (PDL)-tooth specimens were removed and processed to conduct uniaxial compression and tensile tests as well as micro-CT imaging and histological analysis. RESULTS: Three displacements of 0.25, 0.35 and 0.45 mm were obtained from FE analysis and applied in beagles. In general, aligners had poorer performance on movement compared to fixed systems in vivo, but the aligner with a staging of 0.35 mm had the highest accuracy (67.46%) (P < 0.01). Loaded with severe force, fixed sites exhibited tissue damage due to excess force and rapid movement, while aligners showed better safety. The PDL under a 0.35-mm aligner treatment had the highest elastic modulus in the biomechanical test (551.4275 and 1298.305 kPa) (P < 0.05). CONCLUSIONS: Compared to fixed appliances, aligners achieve slightly slower movement but better periodontal condition. Aligners with an interval of 0.35 mm have the highest accuracy and best PDL biomechanical and biological capacities, achieving the most effective and safest movement. Even with complexity of oral cavity and lack of evaluation of other factors, these results provide insight into faster displacement as a method to improve the efficacy of aligners. Elsevier 2023-04-11 /pmc/articles/PMC10126945/ /pubmed/37113787 http://dx.doi.org/10.1016/j.heliyon.2023.e15317 Text en © 2023 Published by Elsevier Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Research Article
Wang, Yuru
Chen, Jie
Qin, Siwen
Han, Xue
Liao, Lijun
Sima, Xiutian
Guo, Weihua
An in vivo evaluation of clear aligners for optimal orthodontic force and movement to determine high-efficacy and periodontal-friendly aligner staging
title An in vivo evaluation of clear aligners for optimal orthodontic force and movement to determine high-efficacy and periodontal-friendly aligner staging
title_full An in vivo evaluation of clear aligners for optimal orthodontic force and movement to determine high-efficacy and periodontal-friendly aligner staging
title_fullStr An in vivo evaluation of clear aligners for optimal orthodontic force and movement to determine high-efficacy and periodontal-friendly aligner staging
title_full_unstemmed An in vivo evaluation of clear aligners for optimal orthodontic force and movement to determine high-efficacy and periodontal-friendly aligner staging
title_short An in vivo evaluation of clear aligners for optimal orthodontic force and movement to determine high-efficacy and periodontal-friendly aligner staging
title_sort in vivo evaluation of clear aligners for optimal orthodontic force and movement to determine high-efficacy and periodontal-friendly aligner staging
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126945/
https://www.ncbi.nlm.nih.gov/pubmed/37113787
http://dx.doi.org/10.1016/j.heliyon.2023.e15317
work_keys_str_mv AT wangyuru aninvivoevaluationofclearalignersforoptimalorthodonticforceandmovementtodeterminehighefficacyandperiodontalfriendlyalignerstaging
AT chenjie aninvivoevaluationofclearalignersforoptimalorthodonticforceandmovementtodeterminehighefficacyandperiodontalfriendlyalignerstaging
AT qinsiwen aninvivoevaluationofclearalignersforoptimalorthodonticforceandmovementtodeterminehighefficacyandperiodontalfriendlyalignerstaging
AT hanxue aninvivoevaluationofclearalignersforoptimalorthodonticforceandmovementtodeterminehighefficacyandperiodontalfriendlyalignerstaging
AT liaolijun aninvivoevaluationofclearalignersforoptimalorthodonticforceandmovementtodeterminehighefficacyandperiodontalfriendlyalignerstaging
AT simaxiutian aninvivoevaluationofclearalignersforoptimalorthodonticforceandmovementtodeterminehighefficacyandperiodontalfriendlyalignerstaging
AT guoweihua aninvivoevaluationofclearalignersforoptimalorthodonticforceandmovementtodeterminehighefficacyandperiodontalfriendlyalignerstaging
AT wangyuru invivoevaluationofclearalignersforoptimalorthodonticforceandmovementtodeterminehighefficacyandperiodontalfriendlyalignerstaging
AT chenjie invivoevaluationofclearalignersforoptimalorthodonticforceandmovementtodeterminehighefficacyandperiodontalfriendlyalignerstaging
AT qinsiwen invivoevaluationofclearalignersforoptimalorthodonticforceandmovementtodeterminehighefficacyandperiodontalfriendlyalignerstaging
AT hanxue invivoevaluationofclearalignersforoptimalorthodonticforceandmovementtodeterminehighefficacyandperiodontalfriendlyalignerstaging
AT liaolijun invivoevaluationofclearalignersforoptimalorthodonticforceandmovementtodeterminehighefficacyandperiodontalfriendlyalignerstaging
AT simaxiutian invivoevaluationofclearalignersforoptimalorthodonticforceandmovementtodeterminehighefficacyandperiodontalfriendlyalignerstaging
AT guoweihua invivoevaluationofclearalignersforoptimalorthodonticforceandmovementtodeterminehighefficacyandperiodontalfriendlyalignerstaging