APOBEC mutagenesis and selection for NFE2L2 contribute to the origin of lung squamous-cell carcinoma

Lung squamous-cell carcinoma originates as a consequence of oncogenic molecular variants arising from diverse mutagenic processes such as tobacco, defective homologous recombination, aging, and cytidine deamination by APOBEC proteins. Only some of the many variants generated by these processes actua...

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Detalles Bibliográficos
Autores principales: Cannataro, Vincent L., Kudalkar, Shalley, Dasari, Krishna, Gaffney, Stephen G., Lazowski, Heather M., Jackson, Laura K., Yildiz, Isil, Das, Rahul K., Rothberg, Bonnie E. Gould, Anderson, Karen S., Townsend, Jeffrey P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126952/
https://www.ncbi.nlm.nih.gov/pubmed/35872531
http://dx.doi.org/10.1016/j.lungcan.2022.07.004

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