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In vitro Reconstitution of Phase-separated p62 Bodies on the Arp2/3-derived Actin Network
In cells, p62/SQSTM1 undergoes liquid–liquid phase separation (LLPS) with poly-ubiquitin chains to form p62 bodies that work as a hub for various cellular events, including selective autophagy. Cytoskeleton components such as Arp2/3-derived branched actin network and motor protein myosin 1D have bee...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Bio-Protocol
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127039/ https://www.ncbi.nlm.nih.gov/pubmed/37113335 http://dx.doi.org/10.21769/BioProtoc.4656 |