A breakdown of metabolic reprogramming in microglia induced by CKLF1 exacerbates immune tolerance in ischemic stroke

Ischemic stroke is characterized by the presence of reactive microglia. However, its precise involvement in stroke etiology is still unknown. We used metabolic profiling and showed that chemokine like factor 1 (CKLF1) causes acute microglial inflammation and metabolic reprogramming from oxidative ph...

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Detalles Bibliográficos
Autores principales: Ma, Wen-yu, Wu, Qing-lin, Wang, Sha-sha, Wang, Hong-yun, Ye, Jun-rui, Sun, Hong-shuo, Feng, Zhong-ping, He, Wen-bin, Chu, Shi-feng, Zhang, Zhao, Chen, Nai-hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127063/
https://www.ncbi.nlm.nih.gov/pubmed/37098609
http://dx.doi.org/10.1186/s12974-023-02779-w

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