Trapoxin A Analogue as a Selective Nanomolar Inhibitor of HDAC11

[Image: see text] Histone deacetylases (HDACs) are enzymes that regulate many important biological pathways. There is a need for the development of isoform-selective HDAC inhibitors for further biological applications. Here, we report the development of trapoxin A analogues as potent and selective i...

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Detalles Bibliográficos
Autores principales: Ho, Thanh Tu, Peng, Changmin, Seto, Edward, Lin, Hening
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127203/
https://www.ncbi.nlm.nih.gov/pubmed/36977486
http://dx.doi.org/10.1021/acschembio.2c00840

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127203/
https://www.ncbi.nlm.nih.gov/pubmed/36977486
http://dx.doi.org/10.1021/acschembio.2c00840

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