Cargando…
Trapoxin A Analogue as a Selective Nanomolar Inhibitor of HDAC11
[Image: see text] Histone deacetylases (HDACs) are enzymes that regulate many important biological pathways. There is a need for the development of isoform-selective HDAC inhibitors for further biological applications. Here, we report the development of trapoxin A analogues as potent and selective i...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127203/ https://www.ncbi.nlm.nih.gov/pubmed/36977486 http://dx.doi.org/10.1021/acschembio.2c00840 |