Identification of a Novel Small Molecule That Enhances the Release of Extracellular Vesicles with Immunostimulatory Potency via Induction of Calcium Influx

[Image: see text] Extracellular vesicles (EVs) transfer antigens and immunomodulatory molecules in immunologic synapses as a part of intracellular communication, and EVs equipped with immunostimulatory functions have been utilized for vaccine formulation. Hence, we sought small-molecule compounds th...

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Detalles Bibliográficos
Autores principales: Sako, Yukiya, Sato-Kaneko, Fumi, Shukla, Nikunj M., Yao, Shiyin, Belsuzarri, Masiel M., Chan, Michael, Saito, Tetsuya, Lao, Fitzgerald S., Kong, Helen, Puffer, Marina, Messer, Karen, Pu, Minya, Cottam, Howard B., Carson, Dennis A., Hayashi, Tomoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127211/
https://www.ncbi.nlm.nih.gov/pubmed/37039433
http://dx.doi.org/10.1021/acschembio.3c00134

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