Impact of sample history and solvent effects on pathway control in the supramolecular polymerisation of Au(i)-metallopeptide amphiphiles

We investigate the kinetics of the supramolecular polymerisation of an Au(i)-metallopeptide amphiphile that assembles into exceptionally long and rigid nanofibers. We developed a precise preparation protocol to measure the concentration dependent assembly kinetics which elucidated a nucleation–elong...

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Detalles Bibliográficos
Autores principales: Thomas, Marius, Lewe, Vanessa, Kölsch, Jonas, Urschbach, Moritz, Erlenbusch, Jessica, Stach, Oliver Sven, Besenius, Pol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127225/
https://www.ncbi.nlm.nih.gov/pubmed/37124957
http://dx.doi.org/10.1039/d3py00053b
Descripción
Sumario:We investigate the kinetics of the supramolecular polymerisation of an Au(i)-metallopeptide amphiphile that assembles into exceptionally long and rigid nanofibers. We developed a precise preparation protocol to measure the concentration dependent assembly kinetics which elucidated a nucleation–elongation dominated supramolecular polymerisation process. We show striking differences in the assembly behavior and morphology in aqueous media, even at organic solvent contents as low as 1 vol%, compared to pure buffer.

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