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Kinetic evidence in favor of glyoxalase III and against deglycase activity of DJ‐1
DJ‐1, a protein encoded by PARK7 plays a protective role against neurodegeneration. Since its glyoxalase III activity catalyzing methylglyoxal (MG) to lactate was discovered, DJ‐1 has been re‐established as a deglycase decomposing the MG‐intermediates with amino acids and nucleotides (hemithioacetal...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127264/ https://www.ncbi.nlm.nih.gov/pubmed/37060572 http://dx.doi.org/10.1002/pro.4641 |