Kinetic evidence in favor of glyoxalase III and against deglycase activity of DJ‐1

DJ‐1, a protein encoded by PARK7 plays a protective role against neurodegeneration. Since its glyoxalase III activity catalyzing methylglyoxal (MG) to lactate was discovered, DJ‐1 has been re‐established as a deglycase decomposing the MG‐intermediates with amino acids and nucleotides (hemithioacetal...

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Detalles Bibliográficos
Autores principales: Choi, Joonhyeok, Tak, Sungho, Jung, Hoe‐Myung, Cha, Soyoung, Hwang, Eunha, Lee, Donghan, Lee, Joon‐Hwa, Ryu, Kyoung‐Seok, Park, Chankyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127264/
https://www.ncbi.nlm.nih.gov/pubmed/37060572
http://dx.doi.org/10.1002/pro.4641

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