Rational Design of Phosphorylation-Responsive Coiled Coil-Peptide Assemblies

[Image: see text] De novo peptides and proteins that switch state in response to chemical and physical cues would advance protein design and synthetic biology. Here we report two designed systems that disassemble and reassemble upon site-specific phosphorylation and dephosphorylation, respectively....

Descripción completa

Detalles Bibliográficos
Autores principales: Thompson, Harry F., Beesley, Joseph L., Langlands, Hannah D., Edgell, Caitlin L., Savery, Nigel J., Woolfson, Derek N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127268/
https://www.ncbi.nlm.nih.gov/pubmed/36988263
http://dx.doi.org/10.1021/acssynbio.3c00064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127268/
https://www.ncbi.nlm.nih.gov/pubmed/36988263
http://dx.doi.org/10.1021/acssynbio.3c00064

Ejemplares similares