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Tau in cerebrospinal fluid induces neuronal hyperexcitability and alters hippocampal theta oscillations
Alzheimer’s disease (AD) and other tauopathies are characterized by the aggregation of tau into soluble and insoluble forms (including tangles and neuropil threads). In humans, a fraction of both phosphorylated and non-phosphorylated N-terminal to mid-domain tau species, are secreted into cerebrospi...
Autores principales: | Brown, Jessica, Camporesi, Elena, Lantero-Rodriguez, Juan, Olsson, Maria, Wang, Alice, Medem, Blanca, Zetterberg, Henrik, Blennow, Kaj, Karikari, Thomas K., Wall, Mark, Hill, Emily |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127378/ https://www.ncbi.nlm.nih.gov/pubmed/37095572 http://dx.doi.org/10.1186/s40478-023-01562-5 |
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