PhiReX 2.0: A Programmable and Red Light-Regulated CRISPR-dCas9 System for the Activation of Endogenous Genes in Saccharomyces cerevisiae

[Image: see text] Metabolic engineering approaches do not exclusively require fine-tuning of heterologous genes but oftentimes also modulation or even induction of host gene expression, e.g., in order to rewire metabolic fluxes. Here, we introduce the programmable red light switch PhiReX 2.0, which...

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Detalles Bibliográficos
Autores principales: Machens, Fabian, Ran, Guangyao, Ruehmkorff, Ciaran, Meyer auf der Heyde, Julie, Mueller-Roeber, Bernd, Hochrein, Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127447/
https://www.ncbi.nlm.nih.gov/pubmed/37014634
http://dx.doi.org/10.1021/acssynbio.2c00517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127447/
https://www.ncbi.nlm.nih.gov/pubmed/37014634
http://dx.doi.org/10.1021/acssynbio.2c00517

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