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Comprehensive single-cell transcriptomic and proteomic analysis reveals NK cell exhaustion and unique tumor cell evolutionary trajectory in non-keratinizing nasopharyngeal carcinoma

BACKGROUND: Nonkeratinizing nasopharyngeal carcinoma (NK-NPC) has a strong association with Epstein-Barr virus (EBV) infection. The role of NK cells and the tumor cell evolutionary trajectory in NK-NPC remain unclear. In this study, we aim to investigate the function of NK cell and the evolutionary...

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Detalles Bibliográficos
Autores principales:	Chen, Cuimin, Wang, Chun, Pang, Ruifang, Liu, Huanyu, Yin, Weihua, Chen, Jiakang, Tao, Lili
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127506/ https://www.ncbi.nlm.nih.gov/pubmed/37098551 http://dx.doi.org/10.1186/s12967-023-04112-8

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