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Gac Is a Transcriptional Repressor of the Lyme Disease Spirochete’s OspC Virulence-Associated Surface Protein

The OspC outer-surface lipoprotein is essential for the Lyme disease spirochete’s initial phase of vertebrate infection. Bacteria within the midguts of unfed ticks do not express OspC but produce high levels when ticks begin to ingest blood. Lyme disease spirochetes cease production of OspC within 1...

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Detalles Bibliográficos
Autores principales: Castro-Padovani, Tatiana N., Saylor, Timothy C., Husted, Olivia T., Krusenstjerna, Andrew C., Jusufovic, Nerina, Stevenson, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127594/
https://www.ncbi.nlm.nih.gov/pubmed/36920207
http://dx.doi.org/10.1128/jb.00440-22