Cargando…

The effect of CFTR modulators on structural lung disease in cystic fibrosis

Background: Newly developed quantitative chest computed tomography (CT) outcomes designed specifically to assess structural abnormalities related to cystic fibrosis (CF) lung disease are now available. CFTR modulators potentially can reduce some structural lung abnormalities. We aimed to investigate...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mok, L. Clara, Garcia-Uceda, Antonio, Cooper, Matthew N., Kemner-Van De Corput, Mariette, De Bruijne, Marleen, Feyaerts, Nathalie, Rosenow, Tim, De Boeck, Kris, Stick, Stephen, Tiddens, Harm A. W. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127680/ https://www.ncbi.nlm.nih.gov/pubmed/37113757 http://dx.doi.org/10.3389/fphar.2023.1147348

Ejemplares similares

Chest computed tomography outcomes in a randomized clinical trial in cystic fibrosis: Lessons learned from the first ataluren phase 3 study
por: Tiddens, Harm A. W. M., et al.
Publicado: (2020)

The development of bronchiectasis on chest computed tomography in children with cystic fibrosis: can pre-stages be identified?
por: Tepper, Leonie A., et al.
Publicado: (2016)

The clinical impact of Lumacaftor-Ivacaftor on structural lung disease and lung function in children aged 6–11 with cystic fibrosis in a real-world setting
por: McNally, Paul, et al.
Publicado: (2023)

Diagnosis of bronchiectasis and airway wall thickening in children with cystic fibrosis: Objective airway-artery quantification
por: Kuo, Wieying, et al.
Publicado: (2017)

Automatic airway segmentation from computed tomography using robust and efficient 3-D convolutional neural networks
por: Garcia-Uceda, Antonio, et al.
Publicado: (2021)

Creating a training set for artificial intelligence from initial segmentations of airways
por: Dudurych, Ivan, et al.
Publicado: (2021)

Airway tapering: an objective image biomarker for bronchiectasis
por: Kuo, Wieying, et al.
Publicado: (2020)

Antisense oligonucleotide eluforsen improves CFTR function in F508del cystic fibrosis
por: Sermet-Gaudelus, Isabelle, et al.
Publicado: (2018)

Cystic Fibrosis, CFTR, and Colorectal Cancer
por: Scott, Patricia, et al.
Publicado: (2020)

Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation
por: Stefano, Daniela De, et al.
Publicado: (2014)

Disease-specific clinical trials networks: the example of cystic fibrosis
por: De Boeck, Kris, et al.
Publicado: (2016)

Assessment of early lung disease in young children with CF: A comparison between pressure‐controlled and free‐breathing chest computed tomography
por: Oudraad, Merel C. J., et al.
Publicado: (2020)

Assessment of p.Phe508del-CFTR functional restoration in pediatric primary cystic fibrosis airway epithelial cells
por: Sutanto, Erika N., et al.
Publicado: (2018)

CFTR and Ca(2+) Signaling in Cystic Fibrosis
por: Antigny, Fabrice, et al.
Publicado: (2011)

Strategies to circumvent the CFTR defect in cystic fibrosis
por: Becq, Frédéric, et al.
Publicado: (2013)

Not All Is CFTR – Neutrophils and Cholesterol in Cystic Fibrosis
por: Castellani, Stefano, et al.
Publicado: (2017)

Cystic Fibrosis and Oxidative Stress: The Role of CFTR
por: Moliteo, Evelina, et al.
Publicado: (2022)

CFTR modulators: transformative therapies for cystic fibrosis
por: Dwight, Mary, et al.
Publicado: (2021)

Analysis of Granulomatous Lymphocytic Interstitial Lung Disease Using Two Scoring Systems for Computed Tomography Scans—A Retrospective Cohort Study
por: Meerburg, Jennifer J., et al.
Publicado: (2020)

A screening tool to identify risk for bronchiectasis progression in children with cystic fibrosis
por: Caudri, Daan, et al.
Publicado: (2021)

Crowdsourcing airway annotations in chest computed tomography images
por: Cheplygina, Veronika, et al.
Publicado: (2021)

Nasal Potential Difference in Cystic Fibrosis considering Severe CFTR Mutations
por: Ng, Ronny Tah Yen, et al.
Publicado: (2015)

CFTR Modulator Therapies: Potential Impact on Airway Infections in Cystic Fibrosis
por: Saluzzo, Francesca, et al.
Publicado: (2022)

Inflammation and CFTR: might neutrophils be the key in cystic fibrosis?
por: Witko-Sarsat, V, et al.
Publicado: (1999)

Fixing cystic fibrosis by correcting CFTR domain assembly
por: Okiyoneda, Tsukasa, et al.
Publicado: (2012)

Targeted therapies to improve CFTR function in cystic fibrosis
por: Brodlie, Malcolm, et al.
Publicado: (2015)

Lived experiences of individuals with cystic fibrosis on CFTR-modulators
por: Page, Annelise, et al.
Publicado: (2022)

The Effect of CFTR Modulators on Airway Infection in Cystic Fibrosis
por: Harvey, Caitlyn, et al.
Publicado: (2022)

Nutritional impact of CFTR modulators in children with cystic fibrosis
por: Gaschignard, Margaux, et al.
Publicado: (2023)

Cross‐talk between CFTR and sphingolipids in cystic fibrosis
por: Dobi, Dorina, et al.
Publicado: (2023)

Analysis of the CFTR gene in Venezuelan cystic fibrosis patients, identification of six novel cystic fibrosis-causing genetic variants
por: Sánchez, Karen, et al.
Publicado: (2016)

Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Allelic Variants Relate to Shifts in Faecal Microbiota of Cystic Fibrosis Patients
por: Schippa, Serena, et al.
Publicado: (2013)

Longitudinal lung clearance index and association with structural lung damage in children with cystic fibrosis
por: Svedberg, Marcus, et al.
Publicado: (2023)

Chest radiography and computed tomography imaging in cystic fibrosis: current challenges and new perspectives
por: Ciet, Pierluigi, et al.
Publicado: (2022)

Predictors of Reduced Survival for Adult-diagnosed Cystic Fibrosis: Older Age at Diagnosis, a Substitute for Older Age?
por: Fieuws, Steffen, et al.
Publicado: (2019)

Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Ubiquitylation as a Novel Pharmaceutical Target for Cystic Fibrosis
por: Fukuda, Ryosuke, et al.
Publicado: (2020)

A Comparative Analysis of Pricing and Reimbursement of Cystic Fibrosis Transmembrane Conductance Regulator Modulators in Europe
por: Abdallah, Khadidja, et al.
Publicado: (2021)

Molecular Chaperones as Targets to Circumvent the CFTR Defect in Cystic Fibrosis
por: Chanoux, Rebecca A., et al.
Publicado: (2012)

Predicting CFTR activity with front-runner cystic fibrosis drugs
por: Becq, Frédéric
Publicado: (2015)

The importance of CFTR expression for neutrophil function in patients with Cystic Fibrosis
por: Jundi, B, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_frjhnljgi3tgo3ccf6mlnmnrsr