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Higher Complication Rate in COVID-19 Recovered Patients Undergoing Primary Total Joint Arthroplasty

BACKGROUND: There is limited data reviewing complication risks associated with total joint arthroplasty (TJA) after recovering from COVID-19. This study evaluated complications within 90 days of TJA in patients who had a COVID-19 diagnosis at varying intervals prior to surgery versus a non-COVID-19...

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Autores principales: Lee, Anderson, Durst, Caleb R., Rezzadeh, Kevin T., Rajaee, Sean S., Penenberg, Brad L., Than, Justin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127742/
https://www.ncbi.nlm.nih.gov/pubmed/37105327
http://dx.doi.org/10.1016/j.arth.2023.04.043
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author Lee, Anderson
Durst, Caleb R.
Rezzadeh, Kevin T.
Rajaee, Sean S.
Penenberg, Brad L.
Than, Justin P.
author_facet Lee, Anderson
Durst, Caleb R.
Rezzadeh, Kevin T.
Rajaee, Sean S.
Penenberg, Brad L.
Than, Justin P.
author_sort Lee, Anderson
collection PubMed
description BACKGROUND: There is limited data reviewing complication risks associated with total joint arthroplasty (TJA) after recovering from COVID-19. This study evaluated complications within 90 days of TJA in patients who had a COVID-19 diagnosis at varying intervals prior to surgery versus a non-COVID-19 cohort. METHODS: A large national database was used to identify patients diagnosed with COVID-19 in the six months prior to total hip arthroplasty (THA) or total knee arthroplasty. The incidence of complications within 90 days of surgery was recorded and compared to a COVID-19 negative control group matched 1:3 for age range in 5-year intervals, Charlson Comorbidity Index, and sex. There were 7,780 patients included in the study; 5,840 (75.1%) never diagnosed with COVID-19, 1,390 (17.9%) who had a COVID-19 diagnosis 0 to 3 months prior to surgery, and 550 (7.1%) who had a COVID-19 diagnosis 3 to 6 months prior to surgery. RESULTS: When compared to their COVID negative controls, patients who had a COVID-19 diagnosis 0 to 3 months prior to surgery had significantly higher rates of readmission (14.0 versus 11.1%, P = .001), pneumonia (2.2 versus 0.7%, P < .001), deep vein thrombosis (DVT) (3.3 versus 1.9%, P = .001), kidney failure (2.4 versus 1.4%, P = .006), and acute respiratory distress syndrome (1.4 versus 0.7%, P = .01). Patients who had a COVID-19 diagnosis 3 to 6 months prior to surgery had significantly higher rates of pneumonia (2.0 versus 0.7%, P = .002) and DVT (3.6 versus 1.9%, P = .005) when compared to their COVID negative controls. CONCLUSION: Patients diagnosed with COVID-19 within three months prior to TJA have an increased risk of 90-day postoperative complications. Risk for pneumonia and DVT remains elevated even when surgery was performed as far as 3 to 6 months after COVID-19 diagnosis.
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spelling pubmed-101277422023-04-26 Higher Complication Rate in COVID-19 Recovered Patients Undergoing Primary Total Joint Arthroplasty Lee, Anderson Durst, Caleb R. Rezzadeh, Kevin T. Rajaee, Sean S. Penenberg, Brad L. Than, Justin P. J Arthroplasty 2022 AAHKS Proceedings BACKGROUND: There is limited data reviewing complication risks associated with total joint arthroplasty (TJA) after recovering from COVID-19. This study evaluated complications within 90 days of TJA in patients who had a COVID-19 diagnosis at varying intervals prior to surgery versus a non-COVID-19 cohort. METHODS: A large national database was used to identify patients diagnosed with COVID-19 in the six months prior to total hip arthroplasty (THA) or total knee arthroplasty. The incidence of complications within 90 days of surgery was recorded and compared to a COVID-19 negative control group matched 1:3 for age range in 5-year intervals, Charlson Comorbidity Index, and sex. There were 7,780 patients included in the study; 5,840 (75.1%) never diagnosed with COVID-19, 1,390 (17.9%) who had a COVID-19 diagnosis 0 to 3 months prior to surgery, and 550 (7.1%) who had a COVID-19 diagnosis 3 to 6 months prior to surgery. RESULTS: When compared to their COVID negative controls, patients who had a COVID-19 diagnosis 0 to 3 months prior to surgery had significantly higher rates of readmission (14.0 versus 11.1%, P = .001), pneumonia (2.2 versus 0.7%, P < .001), deep vein thrombosis (DVT) (3.3 versus 1.9%, P = .001), kidney failure (2.4 versus 1.4%, P = .006), and acute respiratory distress syndrome (1.4 versus 0.7%, P = .01). Patients who had a COVID-19 diagnosis 3 to 6 months prior to surgery had significantly higher rates of pneumonia (2.0 versus 0.7%, P = .002) and DVT (3.6 versus 1.9%, P = .005) when compared to their COVID negative controls. CONCLUSION: Patients diagnosed with COVID-19 within three months prior to TJA have an increased risk of 90-day postoperative complications. Risk for pneumonia and DVT remains elevated even when surgery was performed as far as 3 to 6 months after COVID-19 diagnosis. Elsevier Inc. 2023-04-25 /pmc/articles/PMC10127742/ /pubmed/37105327 http://dx.doi.org/10.1016/j.arth.2023.04.043 Text en © 2023 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle 2022 AAHKS Proceedings
Lee, Anderson
Durst, Caleb R.
Rezzadeh, Kevin T.
Rajaee, Sean S.
Penenberg, Brad L.
Than, Justin P.
Higher Complication Rate in COVID-19 Recovered Patients Undergoing Primary Total Joint Arthroplasty
title Higher Complication Rate in COVID-19 Recovered Patients Undergoing Primary Total Joint Arthroplasty
title_full Higher Complication Rate in COVID-19 Recovered Patients Undergoing Primary Total Joint Arthroplasty
title_fullStr Higher Complication Rate in COVID-19 Recovered Patients Undergoing Primary Total Joint Arthroplasty
title_full_unstemmed Higher Complication Rate in COVID-19 Recovered Patients Undergoing Primary Total Joint Arthroplasty
title_short Higher Complication Rate in COVID-19 Recovered Patients Undergoing Primary Total Joint Arthroplasty
title_sort higher complication rate in covid-19 recovered patients undergoing primary total joint arthroplasty
topic 2022 AAHKS Proceedings
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127742/
https://www.ncbi.nlm.nih.gov/pubmed/37105327
http://dx.doi.org/10.1016/j.arth.2023.04.043
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