BCG Vaccination of Health Care Workers Does Not Reduce SARS-CoV-2 Infections nor Infection Severity or Duration: a Randomized Placebo-Controlled Trial

Bacillus Calmette-Guerin (BCG) vaccination has been hypothesized to reduce severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, severity, and/or duration via trained immunity induction. Health care workers (HCWs) in nine Dutch hospitals were randomized to BCG or placebo vaccinatio...

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Detalles Bibliográficos
Autores principales: Claus, Juana, ten Doesschate, Thijs, Gumbs, Cheyenne, van Werkhoven, Cornelis H., van der Vaart, Thomas W., Janssen, Axel B., Smits, Gaby, van Binnendijk, Rob, van der Klis, Fiona, van Baarle, Debbie, Paganelli, Fernanda L., Leavis, Helen, Verhagen, Lilly M., Joosten, Simone A., Bonten, Marc J. M., Netea, Mihai G., van de Wijgert, Janneke H. H. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10128007/
https://www.ncbi.nlm.nih.gov/pubmed/36976004
http://dx.doi.org/10.1128/mbio.00356-23

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