A Comparison of the Pharmacokinetics and Safety of Dapagliflozin Formate, an Ester Prodrug of Dapagliflozin, to Dapagliflozin Propanediol Monohydrate in Healthy Subjects

BACKGROUND: Dapagliflozin formate (DAP-FOR, DA-2811), an ester prodrug of dapagliflozin, was developed to improve the stability and pharmaceutical manufacturing process of dapagliflozin, a sodium-glucose cotransporter-2 inhibitor. PURPOSE: This study aimed to evaluate the pharmacokinetics (PKs) and...

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Detalles Bibliográficos
Autores principales: Kim, Hyun Chul, Lee, Sangmi, Sung, Siyoung, Kim, Eunjin, Jang, In-Jin, Chung, Jae-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Clinical Trial Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10128151/
https://www.ncbi.nlm.nih.gov/pubmed/37113469
http://dx.doi.org/10.2147/DDDT.S404182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10128151/
https://www.ncbi.nlm.nih.gov/pubmed/37113469
http://dx.doi.org/10.2147/DDDT.S404182

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