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Design and statistical optimisation of emulsomal nanoparticles for improved anti-SARS-CoV-2 activity of N-(5-nitrothiazol-2-yl)-carboxamido candidates: in vitro and in silico studies

In this article, emulsomes (EMLs) were fabricated to encapsulate the N-(5-nitrothiazol-2-yl)-carboxamido derivatives (3a–3g) in an attempt to improve their biological availability and antiviral activity. Next, both cytotoxicity and anti-SARS-CoV-2 activities of the examined compounds loaded EMLs (F3...

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Detalles Bibliográficos
Autores principales: Al-Karmalawy, Ahmed A., El-Gamil, Dalia S., El-Shesheny, Rabeh, Sharaky, Marwa, Alnajjar, Radwan, Kutkat, Omnia, Moatasim, Yassmin, Elagawany, Mohamed, Al-Rashood, Sara T., Binjubair, Faizah A., Eldehna, Wagdy M., Noreddin, Ayman M., Zakaria, Mohamed Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10128464/
https://www.ncbi.nlm.nih.gov/pubmed/37092260
http://dx.doi.org/10.1080/14756366.2023.2202357