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Heterozygous inversion breakpoints suppress meiotic crossovers by altering recombination repair outcomes

Heterozygous chromosome inversions suppress meiotic crossover (CO) formation within an inversion, potentially because they lead to gross chromosome rearrangements that produce inviable gametes. Interestingly, COs are also severely reduced in regions nearby but outside of inversion breakpoints even t...

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Detalles Bibliográficos
Autores principales: Li, Haosheng, Berent, Erica, Hadjipanteli, Savannah, Galey, Miranda, Muhammad-Lahbabi, Nigel, Miller, Danny E., Crown, K. Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10128924/
https://www.ncbi.nlm.nih.gov/pubmed/37053290
http://dx.doi.org/10.1371/journal.pgen.1010702