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Case-only exome variation analysis of severe alcohol dependence using a multivariate hierarchical gene clustering approach

BACKGROUND: Variation in genes involved in ethanol metabolism has been shown to influence risk for alcohol dependence (AD) including protective loss of function alleles in ethanol metabolizing genes. We therefore hypothesized that people with severe AD would exhibit different patterns of rare functi...

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Detalles Bibliográficos
Autores principales:	Gentry, Amanda Elswick, Alexander, Jeffry C., Ahangari, Mohammad, Peterson, Roseann E., Miles, Michael F., Bettinger, Jill C., Davies, Andrew G., Groteweil, Mike, Bacanu, Silviu A., Kendler, Kenneth S., Riley, Brien P., Webb, Bradley T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10128939/ https://www.ncbi.nlm.nih.gov/pubmed/37098020 http://dx.doi.org/10.1371/journal.pone.0283985

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