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Potent NKT cell ligands overcome SARS-CoV-2 immune evasion to mitigate viral pathogenesis in mouse models

One of the major pathogenesis mechanisms of SARS-CoV-2 is its potent suppression of innate immunity, including blocking the production of type I interferons. However, it is unknown whether and how the virus interacts with different innate-like T cells, including NKT, MAIT and γδ T cells. Here we rep...

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Detalles Bibliográficos
Autores principales: Lu, Hongjia, Liu, Zhewei, Deng, Xiangxue, Chen, Siyang, Zhou, Ruiting, Zhao, Rongqi, Parandaman, Ramya, Thind, Amarjot, Henley, Jill, Tian, Lei, Yu, Jianhua, Comai, Lucio, Feng, Pinghui, Yuan, Weiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10128965/
https://www.ncbi.nlm.nih.gov/pubmed/36961850
http://dx.doi.org/10.1371/journal.ppat.1011240