Herpes simplex encephalitis in a patient abusing morphine: a case report from Nepal

Herpes simplex encephalitis results from either primary infection with the herpes simplex virus (HSV) or reactivation of latent HSV residing within the nuclei of sensory neurons. Opioid’s administration is known to reactivate HSV infection. CASE PRESENTATION: We report a 46-year-old male who was in...

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Autores principales: KC, Bijay, Bhattarai, Himal B., Shah, Sangam, Bhattarai, Madhur, Uprety, Manish, Jha, Abhishek, Rayamajhi, Sushil, Pant, Subhash, Limbu, Chandra P., Shrestha, Babu R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10129145/
https://www.ncbi.nlm.nih.gov/pubmed/37113868
http://dx.doi.org/10.1097/MS9.0000000000000462
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author KC, Bijay
Bhattarai, Himal B.
Shah, Sangam
Bhattarai, Madhur
Uprety, Manish
Jha, Abhishek
Rayamajhi, Sushil
Pant, Subhash
Limbu, Chandra P.
Shrestha, Babu R.
author_facet KC, Bijay
Bhattarai, Himal B.
Shah, Sangam
Bhattarai, Madhur
Uprety, Manish
Jha, Abhishek
Rayamajhi, Sushil
Pant, Subhash
Limbu, Chandra P.
Shrestha, Babu R.
author_sort KC, Bijay
collection PubMed
description Herpes simplex encephalitis results from either primary infection with the herpes simplex virus (HSV) or reactivation of latent HSV residing within the nuclei of sensory neurons. Opioid’s administration is known to reactivate HSV infection. CASE PRESENTATION: We report a 46-year-old male who was in a rehabilitation center for 17 days for abusing morphine for 2 years. DISCUSSION: Chronic morphine use weakens immune system thereby, making body prone for development of infection. Opioids may reactivate HSV infection because of their immunosuppressive function. CONCLUSION: Herpes simplex encephalitis is a potentially fatal condition but can be treated with early diagnosis and intervention.
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spelling pubmed-101291452023-04-26 Herpes simplex encephalitis in a patient abusing morphine: a case report from Nepal KC, Bijay Bhattarai, Himal B. Shah, Sangam Bhattarai, Madhur Uprety, Manish Jha, Abhishek Rayamajhi, Sushil Pant, Subhash Limbu, Chandra P. Shrestha, Babu R. Ann Med Surg (Lond) Case Reports Herpes simplex encephalitis results from either primary infection with the herpes simplex virus (HSV) or reactivation of latent HSV residing within the nuclei of sensory neurons. Opioid’s administration is known to reactivate HSV infection. CASE PRESENTATION: We report a 46-year-old male who was in a rehabilitation center for 17 days for abusing morphine for 2 years. DISCUSSION: Chronic morphine use weakens immune system thereby, making body prone for development of infection. Opioids may reactivate HSV infection because of their immunosuppressive function. CONCLUSION: Herpes simplex encephalitis is a potentially fatal condition but can be treated with early diagnosis and intervention. Lippincott Williams & Wilkins 2023-04-07 /pmc/articles/PMC10129145/ /pubmed/37113868 http://dx.doi.org/10.1097/MS9.0000000000000462 Text en Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Case Reports
KC, Bijay
Bhattarai, Himal B.
Shah, Sangam
Bhattarai, Madhur
Uprety, Manish
Jha, Abhishek
Rayamajhi, Sushil
Pant, Subhash
Limbu, Chandra P.
Shrestha, Babu R.
Herpes simplex encephalitis in a patient abusing morphine: a case report from Nepal
title Herpes simplex encephalitis in a patient abusing morphine: a case report from Nepal
title_full Herpes simplex encephalitis in a patient abusing morphine: a case report from Nepal
title_fullStr Herpes simplex encephalitis in a patient abusing morphine: a case report from Nepal
title_full_unstemmed Herpes simplex encephalitis in a patient abusing morphine: a case report from Nepal
title_short Herpes simplex encephalitis in a patient abusing morphine: a case report from Nepal
title_sort herpes simplex encephalitis in a patient abusing morphine: a case report from nepal
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10129145/
https://www.ncbi.nlm.nih.gov/pubmed/37113868
http://dx.doi.org/10.1097/MS9.0000000000000462
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