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Emergent surgical interventions in noncritical traumatic long bone fractures and lactate monitoring: a retrospective cohort study

Serum lactate levels have been recommended as a standard in guiding resuscitation and management of post-traumatic orthopedic injuries. Studies have suggested an increased incidence of postoperative complications in trauma patients with injury severity scores (ISSs) greater than 18. However, in trau...

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Autores principales: Hong, Jeffrey, Malkoc, Aldin, Salahpour, Sofia, Wong, David T., Dong, Fanglong, Neeki, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10129179/
https://www.ncbi.nlm.nih.gov/pubmed/37113824
http://dx.doi.org/10.1097/MS9.0000000000000435
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author Hong, Jeffrey
Malkoc, Aldin
Salahpour, Sofia
Wong, David T.
Dong, Fanglong
Neeki, Michael
author_facet Hong, Jeffrey
Malkoc, Aldin
Salahpour, Sofia
Wong, David T.
Dong, Fanglong
Neeki, Michael
author_sort Hong, Jeffrey
collection PubMed
description Serum lactate levels have been recommended as a standard in guiding resuscitation and management of post-traumatic orthopedic injuries. Studies have suggested an increased incidence of postoperative complications in trauma patients with injury severity scores (ISSs) greater than 18. However, in trauma patients without an elevated ISS, the role of lactate in guiding operative timing has not been explored. This study considers the role of lactate measurement with respect to surgical timing and predicting postoperative complications in trauma patients with long bone fractures and an ISS less than 16. MATERIALS AND METHODS: A total of 164 patients, ages 18 and above with long bone fractures and ISS less than 16 were sampled in the last 5 years. Demographic data was ascertained. Patients were placed into two cohorts with a serum preoperative lactate greater than or equal to 2.0 mmol/l and a serum preoperative lactate less than 2.0 mmol/l. Key endpoints included hospital mortality, length of hospitalization (LOH), discharge designation, and postoperative complications. RESULTS: A total of 148 patients had a lactate level less than 2.0 mmol/l and 16 had a lactate greater than or equal to 2.0 mmol/l. There was no significant difference in demographics between these two preoperative lactate groups. There was no statistical difference when considering mortality, discharge designation, LOH, and postoperative complications. CONCLUSION: Lactate levels assist providers in guide resuscitative efforts in trauma patients. However, this study finds that preoperative lactate measurements and efforts made to normalize lactate level are not correlated with mortality, LOH, and postoperative complications in trauma patients with an ISS less than 16. This study does not support preoperative lactate normalization in guiding surgical timing.
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spelling pubmed-101291792023-04-26 Emergent surgical interventions in noncritical traumatic long bone fractures and lactate monitoring: a retrospective cohort study Hong, Jeffrey Malkoc, Aldin Salahpour, Sofia Wong, David T. Dong, Fanglong Neeki, Michael Ann Med Surg (Lond) Original Research Serum lactate levels have been recommended as a standard in guiding resuscitation and management of post-traumatic orthopedic injuries. Studies have suggested an increased incidence of postoperative complications in trauma patients with injury severity scores (ISSs) greater than 18. However, in trauma patients without an elevated ISS, the role of lactate in guiding operative timing has not been explored. This study considers the role of lactate measurement with respect to surgical timing and predicting postoperative complications in trauma patients with long bone fractures and an ISS less than 16. MATERIALS AND METHODS: A total of 164 patients, ages 18 and above with long bone fractures and ISS less than 16 were sampled in the last 5 years. Demographic data was ascertained. Patients were placed into two cohorts with a serum preoperative lactate greater than or equal to 2.0 mmol/l and a serum preoperative lactate less than 2.0 mmol/l. Key endpoints included hospital mortality, length of hospitalization (LOH), discharge designation, and postoperative complications. RESULTS: A total of 148 patients had a lactate level less than 2.0 mmol/l and 16 had a lactate greater than or equal to 2.0 mmol/l. There was no significant difference in demographics between these two preoperative lactate groups. There was no statistical difference when considering mortality, discharge designation, LOH, and postoperative complications. CONCLUSION: Lactate levels assist providers in guide resuscitative efforts in trauma patients. However, this study finds that preoperative lactate measurements and efforts made to normalize lactate level are not correlated with mortality, LOH, and postoperative complications in trauma patients with an ISS less than 16. This study does not support preoperative lactate normalization in guiding surgical timing. Lippincott Williams & Wilkins 2023-04-04 /pmc/articles/PMC10129179/ /pubmed/37113824 http://dx.doi.org/10.1097/MS9.0000000000000435 Text en Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 (https://creativecommons.org/licenses/by-nc-sa/4.0/) License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. http://creativecommons.org/licenses/by-nc-sa/4.0/ (https://creativecommons.org/licenses/by-nc-sa/4.0/)
spellingShingle Original Research
Hong, Jeffrey
Malkoc, Aldin
Salahpour, Sofia
Wong, David T.
Dong, Fanglong
Neeki, Michael
Emergent surgical interventions in noncritical traumatic long bone fractures and lactate monitoring: a retrospective cohort study
title Emergent surgical interventions in noncritical traumatic long bone fractures and lactate monitoring: a retrospective cohort study
title_full Emergent surgical interventions in noncritical traumatic long bone fractures and lactate monitoring: a retrospective cohort study
title_fullStr Emergent surgical interventions in noncritical traumatic long bone fractures and lactate monitoring: a retrospective cohort study
title_full_unstemmed Emergent surgical interventions in noncritical traumatic long bone fractures and lactate monitoring: a retrospective cohort study
title_short Emergent surgical interventions in noncritical traumatic long bone fractures and lactate monitoring: a retrospective cohort study
title_sort emergent surgical interventions in noncritical traumatic long bone fractures and lactate monitoring: a retrospective cohort study
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10129179/
https://www.ncbi.nlm.nih.gov/pubmed/37113824
http://dx.doi.org/10.1097/MS9.0000000000000435
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