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Fast, accurate antibody structure prediction from deep learning on massive set of natural antibodies
Antibodies have the capacity to bind a diverse set of antigens, and they have become critical therapeutics and diagnostic molecules. The binding of antibodies is facilitated by a set of six hypervariable loops that are diversified through genetic recombination and mutation. Even with recent advances...
Autores principales: | Ruffolo, Jeffrey A., Chu, Lee-Shin, Mahajan, Sai Pooja, Gray, Jeffrey J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10129313/ https://www.ncbi.nlm.nih.gov/pubmed/37185622 http://dx.doi.org/10.1038/s41467-023-38063-x |
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