Cargando…

HSP27 modulates tumoural immune evasion by enhancing STAT3-mediated upregulation of PD-L1 and NLRC5 in ovarian cancer

Multiple preclinical studies have demonstrated that the addition of hyperthermia (HT) to immunotherapy could enhance tumour immunogenicity and stimulate an antitumour immune response, primarily via heat shock proteins (HSPs). However, antitumour immune responses are often impeded by immune evasion m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fezza, Maha, Hilal, George, Tahtouh, Roula, Moubarak, Malak, Atallah, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cancer Intelligence 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10129406/ https://www.ncbi.nlm.nih.gov/pubmed/37113720 http://dx.doi.org/10.3332/ecancer.2023.1526

Ejemplares similares

Glucose restriction combined with chemotherapy decreases telomere length and cancer antigen-125 secretion in ovarian carcinoma
por: Antoun, Stephanie, et al.
Publicado: (2020)

Different TP53 mutants in p53 overexpressed epithelial ovarian carcinoma can be associated both with altered and unaltered glycolytic and apoptotic profiles
por: Antoun, Stephanie, et al.
Publicado: (2018)

Upregulation of TGF-β-induced HSP27 by HSP90 inhibitors in osteoblasts
por: Kuroyanagi, Gen, et al.
Publicado: (2022)

Epigenetic hypomethylation and upregulation of NLRC4 and NLRP12 in Kawasaki disease
por: Huang, Ying-Hsien, et al.
Publicado: (2018)

Upregulation of the NLRC4 inflammasome contributes to poor prognosis in glioma patients
por: Lim, Jaejoon, et al.
Publicado: (2019)

Microarray analysis of breast cancer gene expression profiling in response to 2-deoxyglucose, metformin, and glucose starvation
por: Aoun, Rita, et al.
Publicado: (2022)

Hantavirus-Driven PD-L1/PD-L2 Upregulation: An Imperfect Viral Immune Evasion Mechanism
por: Raftery, Martin J., et al.
Publicado: (2018)

RelB upregulates PD-L1 and exacerbates prostate cancer immune evasion
por: Zhang, Yanyan, et al.
Publicado: (2022)

Upregulation of PD‐L1 by SARS‐CoV‐2 promotes immune evasion
por: Huang, Hsiang‐Chi, et al.
Publicado: (2023)

Clinical research ethics review process in Lebanon: efficiency and functions of research ethics committees – results from a descriptive questionnaire-based study
por: Atallah, David, et al.
Publicado: (2018)

The subcellular redistribution of NLRC5 promotes angiogenesis via interacting with STAT3 in endothelial cells
por: Xu, Xu, et al.
Publicado: (2021)

TOPK mediates immune evasion of renal cell carcinoma via upregulating the expression of PD-L1
por: Li, Jinxin, et al.
Publicado: (2023)

Expressions of HSP70 and HSP27 in Hepatocellular Carcinoma
por: Joo, Mee, et al.
Publicado: (2005)

Hsp27 and Hsp70 Expression in Esophageal Squamous
por: Luz, Caio Cesar Floriano, et al.
Publicado: (2017)

Hsp27-Actin Interaction
por: Graceffa, Philip
Publicado: (2011)

NLRC5 Might Promote Endometrial Cancer Progression by Inducing PD-L1 Expression
por: Zhu, Su-ding, et al.
Publicado: (2022)

Overcoming HSP27-mediated resistance by altered dimerization of HSP27 using small molecules
por: Kim, Jee Hye, et al.
Publicado: (2016)

HSP27 is a partner of JAK2-STAT5 and a potential therapeutic target in myelofibrosis
por: Sevin, Margaux, et al.
Publicado: (2018)

LncTUG1 promotes hepatocellular carcinoma immune evasion via upregulating PD-L1 expression
por: Wu, Rongshou, et al.
Publicado: (2023)

Effects of Upregulation of Hsp27 Expression on Oocyte Development and Maturation Derived from Polycystic Ovary Syndrome
por: Cai, Lingbo, et al.
Publicado: (2013)

Effect of Heat Shock Preconditioning on Pressure Injury Prevention via Hsp27 Upregulation in Rat Models
por: Xu, Huiwen, et al.
Publicado: (2022)

Gastrointestinal cancer cells treatment with bevacizumab activates a VEGF autoregulatory mechanism involving telomerase catalytic subunit hTERT via PI3K-AKT, HIF-1α and VEGF receptors
por: Mahfouz, Nadine, et al.
Publicado: (2017)

DKK1 promotes hepatocellular carcinoma inflammation, migration and invasion: Implication of TGF-β1
por: Fezza, Maha, et al.
Publicado: (2019)

COX-2 upregulation by tumour cells post-chemotherapy fuels the immune evasive dark side of cancer inflammation
por: Bell, Charlotte R., et al.
Publicado: (2022)

Roles of NOD1 (NLRC1) and NOD2 (NLRC2) in innate immunity and inflammatory diseases
por: Correa, Ricardo G., et al.
Publicado: (2012)

Investigation of single and synergic effects of NLRC5 and PD-L1 variants on the risk of colorectal cancer
por: Catalano, Calogerina, et al.
Publicado: (2018)

Helicobacter pylori CagA promotes immune evasion of gastric cancer by upregulating PD-L1 level in exosomes
por: Wang, Jinfeng, et al.
Publicado: (2023)

“You only live twice”: multidisciplinary management of catastrophic case in placenta Accreta Spectrum-a case report
por: Atallah, David, et al.
Publicado: (2020)

The Role of Hsp27 in Chemotherapy Resistance
por: Lampros, Marios, et al.
Publicado: (2022)

Atorvastatin protects against contrast-induced nephropathy via anti-apoptosis by the upregulation of Hsp27 in vivo and in vitro
por: He, Xuyu, et al.
Publicado: (2017)

NLRC5, at the Heart of Antigen Presentation
por: Neerincx, Andreas, et al.
Publicado: (2013)

Dexamethasone suppresses immune evasion by inducing GR/STAT3 mediated downregulation of PD-L1 and IDO1 pathways
por: Xiang, Zhen, et al.
Publicado: (2021)

GM-CSF mediates immune evasion via upregulation of PD-L1 expression in extranodal natural killer/T cell lymphoma
por: Rong, Qi-xiang, et al.
Publicado: (2021)

Epigenetically modified AP-2α by DNA methyltransferase facilitates glioma immune evasion by upregulating PD-L1 expression
por: Long, Shengwen, et al.
Publicado: (2023)

HSP27 and HSP70 expression in squamous cell carcinoma: An immunohistochemical study
por: Deyhimi, Parviz, et al.
Publicado: (2012)

NLRP3, NLRC4 and NLRC5 Gene Polymorphisms Associate with Susceptibility of Pulmonary Aspergillosis in Non-Neutropenic Patients
por: Zhong, Jinjin, et al.
Publicado: (2022)

Involvement of STAT3 in immune evasion during lung tumorigenesis
por: Kida, Hiroshi, et al.
Publicado: (2013)

Upregulated HSP27 in human breast cancer cells reduces Herceptin susceptibility by increasing Her2 protein stability
por: Kang, Se Hun, et al.
Publicado: (2008)

Targeting heat shock protein 27 (HspB1) interferes with bone metastasis and tumour formation in vivo
por: Gibert, B, et al.
Publicado: (2012)

Involvement of the NLRC4-Inflammasome in Diabetic Nephropathy
por: Yuan, Fang, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_gf8f61ihr55knil5d9j2vm60ud