Inhibition of TRF2 Leads to Ferroptosis, Autophagic Death, and Apoptosis by Causing Telomere Dysfunction

BACKGROUND: Gastric cancer (GC) is an aggressive malignancy with a high mortality rate and poor prognosis. Telomeric repeat-binding factor 2 (TRF2) is a critical telomere protection protein. Emerging evidence indicates that TRF2 may be an essential treatment option for GC; however, the exact mechani...

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Detalles Bibliográficos
Autores principales: Yang, Qiuhui, Nie, Ziyang, Zhu, Yukun, Hao, Mingying, Liu, Siqi, Ding, Xuelu, Wang, Feng, Wang, Fei, Geng, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10129434/
https://www.ncbi.nlm.nih.gov/pubmed/37113742
http://dx.doi.org/10.1155/2023/6897268

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