431 Evaluating defective Transcription Coupled-Nucleotide Excision Repair as a mechanism for sensorineural hearing loss in a zebrafish model of Cockayne Syndrome

OBJECTIVES/GOALS: The characterization of the zebrafish as an animal model for Cockayne Syndrome may guide us towards role of Transcription-Coupled Nucleotide Excision Repair (TC-NER) defects in sensorineural hearing loss. METHODS/STUDY POPULATION: To examine our model, we have developed a zebrafish...

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Detalles Bibliográficos
Autores principales: Hernandez-Herrera, Gabriel, Dugdale, Joseph, Schimmenti, Lisa A., Clark, Karl, Cotter, Ryan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2023
Materias:
Team Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10129453/
http://dx.doi.org/10.1017/cts.2023.462

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