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485 Modeling gastric mucus layer physiology using human organoids

OBJECTIVES/GOALS: Our goal is to explore the extent to which organoids can serve as models for the protective mechanisms of the stomach–the mucus barrier and the pH gradient across it. We aim to first optimize and validate an organoid-based model of the gastric mucus layer, and then define the cellu...

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Detalles Bibliográficos
Autores principales: Lyon, Katrina, Sidar, Barkan, Dudiak, Cam, Wilking, Jim, Bansil, Rama, Bimczok, Diane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10129455/
http://dx.doi.org/10.1017/cts.2023.495