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485 Modeling gastric mucus layer physiology using human organoids
OBJECTIVES/GOALS: Our goal is to explore the extent to which organoids can serve as models for the protective mechanisms of the stomach–the mucus barrier and the pH gradient across it. We aim to first optimize and validate an organoid-based model of the gastric mucus layer, and then define the cellu...
Autores principales: | Lyon, Katrina, Sidar, Barkan, Dudiak, Cam, Wilking, Jim, Bansil, Rama, Bimczok, Diane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cambridge University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10129455/ http://dx.doi.org/10.1017/cts.2023.495 |
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