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288 Harnessing the potential of transcriptional adaptation as a mechanism for Amyotrophic lateral sclerosis

OBJECTIVES/GOALS: Understanding the mechanism of transcriptional adaptation may contribute to an explanation for variation in clinical manifestations of Amyotrophic lateral sclerosis patient phenotypes. METHODS/STUDY POPULATION: To examine transcriptional adaptation, we utilized gene editing tools i...

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Detalles Bibliográficos
Autores principales:	Gomez, Adriana Morales, Staff, Nathan, Ekker, Stephen C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cambridge University Press 2023
Materias:	Precision Medicine/Health
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10129462/ http://dx.doi.org/10.1017/cts.2023.344

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