Cargando…

449 Progression of silica-induced pulmonary fibrosis is arrested after selective ablation of Col1a1+ fibroblasts

OBJECTIVES/GOALS: Silicosis is a highly fatal progressive fibrotic disease of the lungs characterized by accumulation and persistence of fibroblasts that excessively deposit Collagen1a1. We sought to eliminate Collagen1a1-expressing fibroblasts through a targeted genetic ablation strategy and hypoth...

Descripción completa

Detalles Bibliográficos
Autores principales:	Foster, Daniel G, Javkhlan, Nomin, Wilson, Jasmine, Edelman, Benjamin L., Riches, David W. H., Redente, Elizabeth F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cambridge University Press 2023
Materias:	Team Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10129511/ http://dx.doi.org/10.1017/cts.2023.476

Ejemplares similares

Inhibition of antiapoptotic BCL-2 proteins with ABT-263 induces fibroblast apoptosis, reversing persistent pulmonary fibrosis
por: Cooley, Joseph C., et al.
Publicado: (2023)

Loss of Fas signaling in fibroblasts impairs homeostatic fibrosis resolution and promotes persistent pulmonary fibrosis
por: Redente, Elizabeth F., et al.
Publicado: (2020)

3359 A TL1 Team Approach to Clinician Perspectives on Hoarding Disorder
por: Henderson, Rebecca R, et al.
Publicado: (2019)

424 Clinical Translational Approach to Targeted Therapy in SLC6A1-related Neurodevelopmental Disorder
por: Goodspeed, Kimberly, et al.
Publicado: (2023)

3475 A TL1 Team Approach to CNS-Localized Delivery of Neurotrophic Factors for Treatment of Parkinson’s Disease
por: Gopinath, Adithya, et al.
Publicado: (2019)

4085 TL1 Team Approach to Predicting Short-term and Long-term Effects of Spinal Cord Stimulation
por: See, Kyle, et al.
Publicado: (2020)

66361 TL1 Team Approach to Predicting Response to Spinal Cord Stimulation for Chronic Low Back Pain
por: See, Kyle, et al.
Publicado: (2021)

429 Eribulin Synergizes with STING Agonists by Enhancing Type 1 Interferon Expression and Improves Antitumor Efficacy as Combination Treatment
por: Takahashi-Ruiz, Leila, et al.
Publicado: (2023)

3357 TL1 Team Approach to Using a Combination of Ganglioside 2 and 3 as an Immunoaffinity Target for Circulating Osteosarcoma Cell Detection
por: Fasanya, Henrietta, et al.
Publicado: (2019)

4045 A TL1 Team Approach to Identify Factors Affecting Rural Tobacco Users’ Participation in Research and Quitting Tobacco Use
por: Gebru, Neo, et al.
Publicado: (2020)

4092 TL1 Team Approach to Investigating Host-Microbe Interactions in Cancer Using a 3D Perfusion Culture System
por: Newsome, Rachel Chantal, et al.
Publicado: (2020)

70274 TL1 team approach to investigating the adhesin gene fimH in adherent invasive E. coli induced inflammation and colorectal cancer development
por: Newsome, Rachel C, et al.
Publicado: (2021)

421 A Phase 1 and Randomized Phase 2 Clinical Trial of Selinexor and Temozolomide in Recurrent Glioblastoma Among Adults: The Product of a Successful Team Science Approach
por: Chow, Frances, et al.
Publicado: (2023)

How Do We Know What We Are Missing? Loss of Signaling through CD148 Drives Fibroblast Activation in Pulmonary Fibrosis
por: Redente, Elizabeth F.
Publicado: (2021)

Building the eye care team
por: Ravilla, Thulasiraj, et al.
Publicado: (2014)

Training, certification and accreditation for eye teams
por: Golnick, Karl, et al.
Publicado: (2014)

Tips for team management
por: Thulasiraj, RD
Publicado: (2018)

Leading and managing a team
por: Kiage, Dan
Publicado: (2018)

How to ‘do’ CPD with your team (from the organisation's perspective)
por: Ramasamy, Dhivya, et al.
Publicado: (2017)

3355 The CTSA Institutional website: A higher purpose - Researcher use of institutional Clinical and Translational Science Award (CTSA) website content to assess or promote NCATS CTSA Program Goals.
por: Tafuto, Barbara Ann
Publicado: (2019)

3531 Evaluation of a Team Leadership Assessment Center Study for Scientists
por: Kotarba, Joseph A, et al.
Publicado: (2019)

3566 Longitudinal analysis of research collaborations and emerging networks
por: Dozier, Ann Marie, et al.
Publicado: (2019)

3336 Who’s ready to collaborate? Evaluating new measures of collaboration readiness among early career scholars in the CTSA network
por: Hawk, Larry, et al.
Publicado: (2019)

3222 University of Mississippi Center for Clinical and Translational Science (CCTS): A Catalyst for Clinical and Translational Sciences
por: Ross, Leigh Ann, et al.
Publicado: (2019)

3203 Collaboration in Reappointment, Promotion, and Tenure Guidelines
por: Knapke, Jacqueline, et al.
Publicado: (2019)

3369 Assessment to Action: Engaging network member’s in identifying needs and directions of network improvement
por: Estabrooks, Paul, et al.
Publicado: (2019)

3415 Percent Predicted Peak Exercise Oxygen Pulse Is a Marker of Cardiac Reserve Following Thoracic Radiotherapy
por: Canada, Justin McNair, et al.
Publicado: (2019)

3165 Diseased and Healthy Gastrointestinal Tissue Data Mining requires an Engaged Transdisciplinary team
por: Syed, Sana, et al.
Publicado: (2019)

3184 Development of a Leadership Assessment Scale in Translational Science
por: Vaughan, Roger, et al.
Publicado: (2019)

3072 Scientometric Analysis of the Puerto Rico Clinical and Translational Research Consortium (PRCTRC) Research Publications, 2010-2017
por: Cintrón, Mariela Torres-, et al.
Publicado: (2019)

4375 Developing team science for practical applications of artificial intelligence in health systems to improve value and outcomes: A case study in reducing avoidable emergency department use
por: Manuel, Vladimir G., et al.
Publicado: (2020)

4203 Re-engineering the Approach to Extremely Preterm Breech Deliveries with Student Led Team Science
por: Dangel, Alissa, et al.
Publicado: (2020)

4559 TX TM: Formalization and Institutional Investment in a Model Designed to Advance Research Translational to Community Transformation
por: Akintobi, Tabia Henry, et al.
Publicado: (2020)

4436 A Content Analysis of CTSA Websites: The Identification and Evaluation of CTSA Program Hub Website Content Standards for Knowledge Management of NCATS CTSA Program Goals and Initiatives
por: Tafuto, Barbara Ann, et al.
Publicado: (2020)

4556 Gender homophily in translational collaborations; a network analysis study of investigators at one academic medical center
por: Nooraie, Reza Yousefi, et al.
Publicado: (2020)

4169 The influence of serious mental illness on medical care of patients with lower back pain in the emergency department
por: Lee, Courtney, et al.
Publicado: (2020)

4319 Team Science in Parkinson’s Research: Connecting Clinicians and Computational Teams
por: Smolensky, Luba
Publicado: (2020)

4027 Collaborative Working Retreats for Interdisciplinary Investigators and Engaged Stakeholders as a Tool for Sparking Creativity and Accelerating the Development of Translational Research Projects
por: Borawski, Elaine A, et al.
Publicado: (2020)

4037 Assessing Leadership Skills in Translational Science Training: The Rockefeller University Leadership Survey
por: Vaughan, Roger, et al.
Publicado: (2020)

4265 Effect of individual characteristics, healthcare access, and built environment on care coordination outcomes related to cardiovascular disease risk factors
por: Patil, Sonal J., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_f05n4dcb0a8im4nmq8c7jelca0