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382 The Role of the IL-6-IGF-II Axis in Systemic Sclerosis-Associated Lung Fibrosis

OBJECTIVES/GOALS: Interleukin (IL)-6 is produced in excess in Systemic Sclerosis (SSc). Likewise, microarray analysis of Insulin-like Growth Factor (IGF)-II-treated NL fibroblasts revealed increased expression of the basic helix-loop-helix transcription factor, BHLHB2. Our goal is to delineate the r...

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Detalles Bibliográficos
Autores principales:	Adewale, Adegboyega Timothy, Feghali-Bostwick, Carol
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cambridge University Press 2023
Materias:	Precision Medicine/Health
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10129518/ http://dx.doi.org/10.1017/cts.2023.418

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