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345 The Role of TCF7L2 in Hepatic Metabolic Zonation

OBJECTIVES/GOALS: Single nucleotide polymorphisms in the transcription factor 7-like 2 (TCF7L2) gene are associated with Type 2 Diabetes (T2D) and nonalcoholic fatty liver disease (NAFLD). The metabolic function of TCF7L2 in the liver remains to be fully elucidated, but we hypothesized that TCF7L2 c...

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Detalles Bibliográficos
Autores principales:	Ayala, Iriscilla I., Hebbale, Skanda K, Shannon, Chris E., Valdez, Ivan, Fourcaudot, Marcel, Bakewell, Terry M., Sholto, Madelaine, Vallim, Thomas, Heikkinen, Sami
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cambridge University Press 2023
Materias:	Precision Medicine/Health
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10129540/ http://dx.doi.org/10.1017/cts.2023.389

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