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372 HMGB1 Localization as a Driver of Carcinogenesis in RDEB-Associated Squamous Cell Carcinoma

OBJECTIVES/GOALS: This study investigates whether localization of high mobility group box 1 (HMGB1) controls inflammatory signaling and DNA damage response in human keratinocytes, the cell of origin for squamous cell carcinoma (SCC). SCC is especially metastatic in chronic wounds, burns, and in pati...

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Detalles Bibliográficos
Autores principales:	Bui, Kacey Guenther, Bielinsky, Anja, Nguyen, Hai Dang, Tolar, Jakub
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cambridge University Press 2023
Materias:	Precision Medicine/Health
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10129564/ http://dx.doi.org/10.1017/cts.2023.410

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