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373 Identification of potential targets for immunotherapy in a cynomolgus macaque model of Ebola virus disease
OBJECTIVES/GOALS: Ebola virus infection causes severe disease and liver injury in humans. Macrophages contribute to inflammatory signaling and are prevalent in the liver. We assessed the activation status, including therapeutic target expression, of hepatic macrophages. METHODS/STUDY POPULATION: We...
Autores principales: | Wanninger, Timothy, Saldarriaga, Omar A., Millian, Daniel E., Comer, Jason E., Khanipov, Kamil, Golovko, George, Paessler, Slobodan, Stevenson, Heather L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cambridge University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10129608/ http://dx.doi.org/10.1017/cts.2023.411 |
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