466 Development of a novel tocotrienol analogue, tocoflexol, as a radiomitigator

OBJECTIVES/GOALS: We have designed an analogue of the Vitamin E tocotrienols called tocoflexol, which improves their pharmacokinetic limitations to make it an effective radiation medical countermeasure. Our goal is to demonstrate that tocoflexol is an effective radiomitigator in vivo when administer...

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Detalles Bibliográficos
Autores principales: Shrimali, Shivangi, Singh, Awantika, Manian, Rajeshkumar, Thakkar, Shraddha, Jones, Darin E., Aykin-Burns, Nukhet, Breen, Philip, Compadre, Cesar M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2023
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10129690/
http://dx.doi.org/10.1017/cts.2023.485

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